in Genetic Engineering & Biotechnology News (GEN)
Pediatric dysphagia (swallowing difficulties) is a frequent and serious clinical complication in a large number of clinically defined neurodevelopmental disorders including the genetic childhood disorder DiGeorge syndrome (also known as 22q11.2 deletion syndrome). Using a mouse model of DiGeorge syndrome, researchers uncovered that the motor neurons that directly control the tongue muscles were firing spontaneously, out of sync with the mechanisms that should control their activity….
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